Chinese Journal of Tissue Engineering Research ›› 2018, Vol. 22 ›› Issue (35): 5631-5636.doi: 10.3969/j.issn.2095-4344.1008

Previous Articles     Next Articles

Mechanical properties of intact and defective articular cartilage under rolling load  

Li Zhiqiang1, 2, Gao Lilan1, 2, Si Yunpeng1, 2, Zhang Chunqiu1, 2   

  1. 1Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, School of Mechanical Engineering, Tianjin University of Technology, Tianjin 300384, China; 2National Demonstration Center for Experimental Mechanical and Electrical Engineering Education, Tianjin University of Technology, Tianjin 300384, China
  • Online:2018-12-18 Published:2018-12-18
  • Contact: Corresponding author: Gao Lilan. MD, Associate professor, Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, School of Mechanical Engineering, Tianjin University of Technology, Tianjin 300384, China; National Demonstration Center for Experimental Mechanical and Electrical Engineering Education, Tianjin University of Technology, Tianjin 300384, China Corresponding author: Zhang Chunqiu, MD, Professor, Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, School of Mechanical Engineering, Tianjin University of Technology, Tianjin 300384, China; National Demonstration Center for Experimental Mechanical and Electrical Engineering Education, Tianjin University of Technology, Tianjin 300384, China
  • About author:Li Zhiqiang, Master candidate, Tianjin Key Laboratory for Advanced Mechatronic System Design and Intelligent Control, School of Mechanical Engineering, Tianjin University of Technology, Tianjin 300384, China; National Demonstration Center for Experimental Mechanical and Electrical Engineering Education, Tianjin University of Technology, Tianjin 300384, China
  • Supported by:

    the National Natural Science Foundation of China, No. 11572222, 11672208 and 11432016

PDF

171

Abstract:

BACKGROUND: Knee joint is the main load-bearing tissue during movement and it is also a predilection site for clinical disease. Rolling load makes a great influence on the physiology and pathology of the knee cartilage, but the relative studies are few.

OBJECTIVE: To explore the mechanical properties of intact and defective cartilage tissue under rolling load at different rolling velocities, different compression amounts, and maximum rolling times of 150.
METHODS: The intact and defective cartilage tissues from pig knee were prepared. Different loads were controlled using rolling device. The strains of different layers of the intact and defective cartilage tissues under rolling were studied.
RESULTS AND CONCLUSION: Under rolling load, the normal strains of superficial layers of both intact and defective cartilages were largest, followed by the middle layer, and the deep layer was smallest. The normal strain of each layer near the cartilage defect was greater than that of the intact cartilage. With the increase of compression, the normal strains of different layers of articular cartilage were increased, and the strain of defect cartilage near the defect area was also increases greatly. The faster the rolling rate, the faster the strain reached the maximum stability. In summary, the mechanical properties of different layers of cartilage are affected by rolling velocity, compression and defect. Cartilage defects lead to the increased deformation of the cartilage tissue under rolling loads, which may further aggravate cartilage damage.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Cartilage, Articular, Biomechanics, Tissue Engineering

CLC Number: